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By Target- Retinoid Receptor
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Results for "
le135
" in TargetMol Product Catalog- Inhibitors & Agonists1
LE135
LE 135
T22920155877-83-1
LE135 is a potent RAR antagonist that binds selectively to RARα (Ki of 1.4 μM) and RARβ (Ki of 220 nM), showing higher affinity for RARβ. It is highly selective over RARγ, RXRα, RXRβ, and RXRγ. LE135 also acts as a potent TRPV1 and TRPA1 receptor activator with EC50s of 2.5 μM and 20 μM, respectively.
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