l-menthyl acetate

(-)-Menthyl acetate exhibits broad-spectrum antibacterial activity, with minimum inhibitory concentrations (MIC) ranging from 0.12 to 8.0 μL/mL against pathogenic fungi such as Candida albicans and Aspergillus niger. It also inhibits fungal biofilm formation. (-)-Menthyl acetate enhances the skin permeability of 5-aminoacetopropionic acid, making it a potential tool for studying transdermal drug absorption.

Menthyl acetate is an ester compound and terpenoid derivative widely used in biochemical experiments and drug synthesis research.

(+)-Menthyl acetate, extracted from the essential oil of Cunila angustifolia Benth, exhibits selective cytotoxicity, demonstrating higher efficacy against the MCF-7 cell line with an IC50 of 34.0 μg/mL and lower efficacy against the SK-Mel-28 cell line, where the IC50 is 279.9 μg/mL, when tested on A549 cells without fatal consequences [1].