l-gulono-1,4-lactone

L-Gulono-1,4-lactone, a substrate of L-gulono-1,4-lactone oxidoreductase, catalyzes the final step in the biosynthesis of L-ascorbic (Vitamin) C.

2,3:5,6-Di-O-isopropylidene-L-gulono-1,4-lactone is a biochemical reagent used in glycobiology research. Glycobiology examines the structure, synthesis, biology, and evolution of sugars, involving carbohydrate chemistry, glycan formation and degradation enzymology, protein-glycan interactions, and the role of glycans in biological systems. This field is closely linked with fundamental research, biomedical science, and biotechnology.

5-Azido-6-(tert-butyldimethylsilyl)-2,3-O-isopropylidene L-gulono-1,4-lactone is a biochemical reagent used in glycoscience research. This field investigates the structure, synthesis, biology, and evolution of sugars, covering carbohydrate chemistry, glycan formation and degradation enzymology, protein-glycan interactions, and glycans' roles in biological systems. Glycoscience is closely linked to fundamental research, biomedicine, and biotechnology.

1,4-D-Gulonolactone (D-Gulonic acid γ-lactone) (also known as reduced ascorbic acid, RAA) is the substrate of the enzyme L-gulono-1,4-lactone oxidoreductase (EC 1.1.3.8), which catalyzes the last step of the biosynthesis of L-ascorbic acid (vitamin C) in plants and animals. The enzyme L-Gulono-1,4-lactone oxidase is missing in scurvy-prone, vitamin C-deficient animals, such as humans. 1,4-D-Gulonolactone is present in human blood and has been used as one of the markers to compare changes in exercise-induced oxidative stress.