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k-0859

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    2
    TargetMol | All_Pathways
BGG463
K 0859
T4618890129-26-7
BGG463 (K 0859) can inhibit c-ABL-T334I, BCR-ABL and BCR-ABL-T315I variants with a 50% inhibitory concentration (IC50) of 0.25 μM, 0.09 μM and 0.590 μM, respectively.
  • $56
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TargetMol | Citations Cited
Anacetrapib
MK-0859
T1928875446-37-0
Anacetrapib (MK-0859) (MK0859) is an effective, specific, reversible rhCETP and mutant CETP(C13S) inhibitor (IC50: 7.9 nM and 11.8 nM). Anacetrapib reduces the transfer of cholesteryl ester from HDL to LDL and/or VLDL thereby, producing an increase in serum HDL-cholesterol levels and a decrease in serum LDL-cholesterol levels.
  • $30
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