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(2)
By Target- Apoptosis
- Autophagy(1)
- E1/E2/E3 Enzyme(1)
- HDAC(1)
- Mdm2(1)
- p53(1)
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Results for "
jnj26854165
" in TargetMol Product Catalog- Inhibitors & Agonists2
Serdemetan
JNJ-26854165
T2243881202-45-5
Serdemetan (JNJ-26854165) is an orally bioavailable HDM2 antagonist with potential antineoplastic activity.
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Quisinostat dihydrochloride
Quisinostat 2HCl, Quisinostat (JNJ-26481585) 2HCl, JNJ26854165(Quisinostat) 2HCl, JNJ-26481585 2HCl
T6865875320-31-3
Quisinostat dihydrochloride (JNJ26854165(Quisinostat) 2HCl) is a novel second-generation HDAC inhibitor with highest potency for HDAC1 with IC50 of 0.11 nM in a cell-free assay, modest potent to HDACs 2, 4, 10, and 11; greater than 30-fold selectivity against HDACs 3, 5, 8, and 9 and lowest potency to HDACs 6 and 7. Phase 2.
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