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Results for "
gsk0660
" in TargetMol Product Catalog- Inhibitors & Agonists2
PT-S58
T708861356497-92-1
PT-S58 is a PPAR β δ full antagonist, and a derivative of GSK0660. PT-S58 has a three-fold higher affinity for the receptor than GSK0660 and is a potent inhibitor of agonist-induced target gene expression. PT-S58 are effective on PPRE-independent functions of PPARβ δ. Unlike GSK0660, PT-S58 blocks the recruitment co-repressor molecules such as SMRT.
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