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By Target- E1/E2/E3 Enzyme
- IκB/IKK(1)
- NF-κB(1)
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Results for "
gs143
" in TargetMol Product Catalog- Inhibitors & Agonists1
GS143
GS-143, GS 143
T25465916232-21-8
GS143 is a selective IκBα ubiquitination inhibitor with an IC50 of 5.2 μM for SCFβTrCP1-mediated IκBα ubiquitylation. It suppresses NF-κB activation and transcription of target genes without inhibiting proteasome activity. GS143 has anti-asthm[atic] properties.
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