gly-gly-gly-peg4-dbco

Gly-Gly-Gly-PEG4-DBCO is a degradable ADC linker containing 4 units of PEG, which can be used to synthesize antibody-conjugated active molecules (ADCs).

Gly-Gly-Gly-PEG4-azide is a peptide-PEG hybrid linker used in the synthesis of antibody-drug conjugates (ADCs). Gly-Gly-Gly-PEG4-azide exhibits click chemistry specificity and serves as a click chemistry reagent. Gly-Gly-Gly-PEG4-azide contains an azide group and can undergo a copper-catalyzed azide-alkyne cycloaddition (CuAAc) reaction with molecules containing an alkyne group. Gly-Gly-Gly-PEG4-azide can also undergo a ring-strain-assisted acetylene-azide cycloaddition (SPAAC) reaction with molecules containing DBCO or BCN groups.