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Results for "
glun2b, bms-986169
" in TargetMol Product Catalog- Inhibitors & Agonists2
BMS-986169
BMS986169, BMS 986169
T238081801151-08-5
BMS-986169 is a high-affinity and selective negative allosteric modulator of the NMDA receptor GluN2B subunit, with an IC50 of 24 nM in oocytes, and exhibits antidepressant-like activity in mice, making it a potential treatment for treatment-resistant depression.
- $457
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BMS-986163
T146861801151-09-6
BMS-986163, a negative allosteric modulator of GluN2B, rapidly converts to its active parent molecule BMS-986169 (Ki=4 nM, IC50=24 nM) as a prodrug.
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