glibenclamide potassium

Glibenclamide potassium, also known as Glyburide potassium, is a potassium salt form of Glibenclamide. It is available in both anhydrous and hydrate versions, exhibiting greater solubility than the pure Glibenclamide [1].

Glibenclamide (Glyburide) is an antidiabetic sulfonylurea derivative with actions similar to those of chlorpropamide.

AZ-DF 265 is a hypoglycaemic drug which stimulates insulin release. AZ-DF-265 inhibits ATP-sensitive potassium channels and displaces [3H]-glibenclamide from the sulphonylurea receptor.

Glibenclamide (Standard) is the analytical reference standard of Glibenclamide intended for research and quantitative applications, and as an orally active ATP-sensitive potassium channel inhibitor, Glibenclamide directly binds SUR1 subunits of KATP channels, inhibits P-glycoprotein and CFTR, alters mitochondrial membrane ion permeability, induces autophagy, and supports research in diabetes, obesity, and cellular bioenergetics.