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fubp1-in-1

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  • Inhibitors & Agonists
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FUBP1-IN-1
FUBP1–IN-1
T11332883003-62-1
FUBP1 - in-1, with an IC50 value of 11.0 M, is an effective FUSE binding protein 1 (FUBP1) inhibitor that can interfere with the binding of FUBP1 to its SINGLE-strand target DNA FUSE sequence.
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FUBP1-IN-2
T731661242862-71-0
FUBP1-IN-2 is a potent inhibitor of far upstream binding protein 1 (FUBP1), effectively disrupting the FUBP1-FUSE interaction in the KH4 domain as demonstrated in a gel shift assay. This compound also exhibits binding affinity to FUBP1 in ChIP assays. Furthermore, FUBP1-IN-2 significantly downregulates c-Myc mRNA and protein levels, upregulates p21 mRNA and protein levels, and depletes intracellular polyamines.
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6-8 weeks
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