ferrichrome

Ferrichrome (iron-free) is an iron carrier derived from isoxazolates produced by various fungi, including U. sphaerogena, which enhances iron chelation and absorption in these organisms. In bacteria, Ferrichrome (iron-free) can be utilized as an exogenous iron carrier, such as in Pseudomonas aeruginosa and Vibrio parahaemolyticus. Ferrichrome (iron-free) (0.8 μM) inhibits the proliferation of mouse splenic monocytes induced by concanavalin A and reduces the expression of the IL-2 receptor on CD4+ T cells. Furthermore, Ferrichrome (iron-free) inhibits the heme-catalyzed oxidation of LDL by hydrogen peroxide in a concentration-dependent manner.