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entprostaglandin f2α

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  • Inhibitors & Agonists
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ent-Prostaglandin F2α
ent-Prostaglandin F2α
T3599254483-31-7
ent-Prostaglandin F2α is the enantiomer of PGF2α and is found in urine.
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TargetMol
ent-8-iso-15(S)-Prostaglandin F2α
ent-8-iso-15(S)-Prostaglandin F2α
T35990214748-66-0
Isoprostanes are produced by the non-enzymatic, free radical peroxidation of phospholipid-esterified arachidonic acid. They have been used as biomarkers of oxidative stress, but they also have been found to have potent biological activity. ent-8-iso-15(S)-Prostaglandin F2α (ent-8-iso-15(S)-PGF2α) is a potent vasoconstrictor of porcine retinal and brain microvessels with EC50 values of 15 and 24 nM, respectively. This isoprostane is about ten-fold more potent than 8-iso-PGF2α in a whole blood platelet aggregation inhibition assay.
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10-14 weeks
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