elaidate

Gemcitabine elaidate (CP-4126), is a lipophilic, unsaturated fatty acid ester derivative of gemcitabine (dFdC), an antimetabolite deoxynucleoside analogue, with potential antineoplastic activity. Upon hydrolysis intracellularly by esterases, the prodrug gemcitabine is converted into the active metabolites difluorodeoxycytidine di- and tri-phosphate (dFdCDP and dFdCTP) by deoxycytidine kinase. dFdCDP inhibits ribonucleotide reductase, thereby decreasing the deoxynucleotide pool available for DNA synthesis; dFdCTP is incorporated into DNA, resulting in DNA strand termination and apoptosis.

Gemcitabine elaidate (CP-4126) hydrochloride is a lipophilic pro-drug of Gemcitabine, converted to Gemcitabine by esterases for phosphorylation. Unlike gemcitabine, Gemcitabine elaidate hydrochloride can be administered orally, displaying schedule and dose-dependent toxicity and antitumor activity.

Cholesteryl elaidate is an organic compound classified as an ester. It is formed through a reaction between cholesterol and elaidic acid, resulting in a white crystalline solid with a mild sweet taste. In the pharmaceutical industry, cholesteryl elaidate has numerous applications, particularly as a bioactive compound with potential research roles for addressing various medical conditions such as high cholesterol and inflammation-related diseases. Additionally, it has potential use as a food additive to enhance texture and stability.

4-Methylumbelliferyl elaidate is a biochemical reagent that can be used as a biomaterial for life science related research and as a sulfonylation reagent for organic synthesis and drug discovery.

Methyl elaidate (Elaidic Acid Methyl Ester) is a synthetic fatty acid methyl ester used as an adjuvant in the formulation of plant protection products.

Methyl petroselaidate (methyl (E)-octadec-6-enoate) is a long-chain fatty acid ester commonly used as an industrial lubricant.

Methyl ricinelaidate is a reagent used in biochemical reactions.

Ethyl petroselaidate is a biochemical reagent that can be used as a biomaterial for life science related research and as a sulfonylation reagent for organic synthesis and drug discovery.

Methyl linolelaidate is a natural product.

1-Palmitoyl-2-oleoyl-rac-glycerol, a diacylglycerol, features palmitic acid at the sn-1 position and oleic acid at the sn-2 position. Detected in crude sunflower lecithin, its levels elevate in RINm5F rat insulinoma cells following treatment with oleate, elaidate, or trans-vaccenate.