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eca 9706

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
Dalpiciclib
SHR-6390
T96361637781-04-4
Dalpiciclib (SHR-6390) is a highly selective, orally bioavailable, and comparable potency inhibitor of CDK4 and CKD6 with IC50s of 12.4 nM and 9.9 nM, respectively. Dalpiciclib exerts potent antitumor activity in esophageal squamous cell carcinoma by inhibiting phosphorylated tumor suppressor retinoblastoma protein (Rb) and inducing G1 cell cycle arrest.
  • $152
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Dalpiciclib hydrochloride
T63199
Dalpiciclib (SHR-6390) hydrochloride is a highly selective, orally active CDK4/6 inhibitor with IC50 values of 12.4 nM and 9.9 nM, respectively, acting as an antitumor agent in breast and esophageal squamous cell carcinomas.
  • $1,490
1-2 weeks
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