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Results for "
dotma
" in TargetMol Product Catalog- Inhibitors & Agonists1
- Cell Research1
DOTMA
Trimethyl[2,3-(dioleyloxy)propyl]ammonium Chloride, N-(1-(2,3-dioleyloxy)propyl)-N,N,N-trimethylammonium
T8902104872-42-6
DOTMA (N-(1-(2,3-dioleyloxy)propyl)-N,N,N-trimethylammonium) is a tetra-methylated DOTA analogue. DOTMA is a cationic lipid and can be used as a non-viral vector for gene therapy. It has been used as a component in liposomes that can be used to encapsulate siRNA, microRNAs, and oligonucleotides and for gene transfection in vitro. It exhibits effective in vitro and in vivo gene transfection. DOTMA induces a positive charge on the liposomes and thus promotes efficient liposome- cell membrane interaction.
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