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By Tag By Expression System- E. coli(1)
By Species- Human(1)
By SPR-compatible Buffer- Ready-to-use(1)
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Results for "
dff-1
" in TargetMol Product Catalog- Recombinant Protein1
CompareInhibitor of CAD, ICAD, H13, DNA Fragmentation Factor Subunit α, DNA Fragmentation Factor Subunit Alpha, DNA Fragmentation Factor 45 kDa Subunit, DFFA, DFF-45, DFF45, DFF1
TMPJ-00483
DNA Fragmentation Factor Subunit Alpha (DFFA). DFFA exists as a heterodimer (DFF) with DFFB. DFF is activated once DFFA is cleaved by Caspase-3. The cleaved fragments of DFFA detach from DFFB (the active component of DFF), which in turn triggers DNA fragmentation as well as chromatin condensation during apoptosis. A reduced level of DFFA detected in ovarian endometriosis may be a part of an apoptosis-resistant mechanism enhancing the disease progression.
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