cucurbitacin b

Cucurbitacin B (Cuc B) has profound in vitro and in vivo antiproliferative effects against human pancreatic Y cells. It inhibited AKT signaling activation through up-regulation of PTEN. Cucurbitacin B is an effective inhibitor of HIF-1 and provide new perspectives into the mechanism of its anticancer activity. Cucurbitacin B inhibits proliferation and induces apoptosis via STAT3 pathway inhibition in A549 lung Y cells.

Cucurbitacin B 2-o-α²-D-glucoside has anticancer activity.

2-epi-Cucurbitacin B, a natural product, is derived from Ecballium elaterium L. XVI. [1].

Dihydroisocucurbitacin B, an active compound, can be extracted from the roots of Wilbrandia ebracteata [1].

Dihydrocucurbitacin B (23,24-dihydrocucurbitacin B) is isolated from the roots of Cayaponia tayuya with anti-cancer activity.

Isocucurbitacin B has significant activities against HeLa and HT-29 human cancer cells with IC50 values ranging from 0.93 to 9.73uM.

3-epi-Isocucurbitacin B is a natural product for research related to life sciences. The catalog number is TN5972 and the CAS number is 89647-62-1.

7β-Hydroxycucurbitacin B is a natural product for research related to life sciences. The catalog number is TN5978 and the CAS number is 1135141-79-5.

Cucurbitacin I (JSI-124), a natural compound, is a selective inhibitor of JAK2 STAT3 with anti-cancer activity.

Cucurbitacin A 2-O-β-D-glucopyranoside is a natural product for research related to life sciences. The catalog number is TN5974 and the CAS number is 1135141-76-2.