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ct 707

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
Conteltinib
SY-707, CT-707
T149971384860-29-0In house
Conteltinib (CT-707) is an enzyme inhibitor with antitumor activity targeting FAK, ALK, and Pyk2.Conteltinib exhibits significant inhibition of FAK, overcomes hypoxia-mediated sorafenib resistance in hepatocellular carcinoma through inhibition of YAP signaling, and can be used in advanced ALK-positive non-small-cell lung cancer and lymphoma.
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6-8 weeks
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Conteltinib tetrahydrochloride
CT-707 tetrahydrochloride, Conteltinib tetrahydrochloride
T204589
Conteltinibtetrahydrochloride (CT-707 tetrahydrochloride) is the tetrahydrochloride form of Conteltinib. It acts as an inhibitor for FAK (IC50=1.6 nM), ALK, and Pyk2. When used in combination with Cabozantinib, Conteltinib tetrahydrochloride exhibits a synergistic antitumor effect.
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7-10 days
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