ch2cooh-peg3-ch2cooh

CH2COOH-PEG3-CH2COOH is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation through the ubiquitin-proteasome system within cells.

Boc-NH-PEG3-CH2COOH, a PEG-based PROTAC linker, can be utilized in PROTAC synthesis [1].

Cbz-NH-PEG3-CH2COOH is a PEG-based PROTAC linker utilized in the synthesis of PROTACs (Proteolysis Targeting Chimeras).

PEG3-O-CH2COOH (PROTAC Linker 8) is a PEG-based linker utilized in the synthesis of SNIPERs.

Amino-PEG3-CH2COOH is a PEG-based linker for PROTACs that joins two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

Br-PEG3-CH2COOH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Fmoc-amino-PEG3-CH2COOH, a polyethylene glycol (PEG)-based linker, is primarily used in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

m-PEG3-CH2COOH is a PEG-based linker used in PROTACs that connects two essential ligands to facilitate the formation of PROTAC molecules, thereby enabling selective protein degradation through the ubiquitin-proteasome system within cells.

Propargyl-PEG3-CH2COOH is a PEG-based PROTAC linker utilized in PROTAC synthesis[1].

N3-PEG3-CH2COOH (PROTAC Linker 14) is a PEG-based compound employed in PROTAC synthesis.

Tos-PEG3-CH2COOH is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Biotin-PEG3-CH2COOH is a PEG-based linker for PROTACs, joining two essential ligands crucial for forming PROTAC molecules and enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

t-Butyl acetate-PEG3-CH2COOH is a polyethylene glycol-derived PROteolysis TArgeting Chimera (PROTAC) linker designed for incorporation into the synthesis of PROTAC molecules.

CEP1347-VHL-02 is a PROTAC that selectively targets MLK3. This compound is composed of the target protein ligand CEP-1347, the E3 ubiquitin ligase ligand (S,R,S)-AHPC-Me, and the PROTAC linker Amino-PEG3-CH2COOH. The participating component responsible for controlling the target protein ligand activity is CEP-1347-acid, whereas the conjugate of the E3 ubiquitin ligase ligand and linker is identified as (S,R,S)-AHPC-Me-CO-CH2-PEG3-NH2.