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cerk

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  • Inhibitors & Agonists
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    TargetMol | All_Pathways
  • PROTAC Products
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    TargetMol | PROTAC
NVP 231
T1933362003-83-6
NVP-231 is a potent, specific and reversible CerK inhibitor(IC50=12±2 nM) that competitively inhibits ceramide binding to CerK.
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PROTAC ERK5 degrader-1
T2108072919963-24-7
PROTACERK5 degrader-1 (compound 2) is a bifunctional ERK5 PROTAC degrader. It induces the degradation of ERK5 in MOLT-4 cells via a VHL-mediated proteasome pathway. PROTACERK5 degrader-1 is useful for studying diseases or disorders characterized by abnormal ERK5 activity.
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