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cdk8/19-in-1

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
  • PROTAC Products
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    TargetMol | PROTAC
CDK8/19-IN-1
T107391818427-07-4
CDK8 19-IN-1 is a selective, orally bioavailable dual inhibitor of CDK8 and CDK19, with IC50 values of 0.46 nM for CDK8, 0.99 nM for CDK19, and 270 nM for [CDK9].
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6-8 weeks
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SNX7886
T811372924557-42-4
SNX7886 is a potent PROTAC (proteolysis-targeting chimera) that effectively degrades CDK8 and CDK19, achieving 90% degradation of CDK8 and 80% degradation of CDK19 in 293 cells [1].
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