carrageenin

Alnustone ((4E,6E)-1,7-Diphenyl-4,6-heptadien-3-one) exerts significant anti-inflammatory activity in the assay of carrageenin-induced hind paw edema in rats.

1. Yunaconitine (Guayewuanine B) has anti-inflammatory and analgesic actions. 2. Yunaconitine was shown to have anti-thermic effect in pyrexial rats when administered orally at a dose of 5 μg kg. 3. Yunaconitine shows positive effect in the granuloma inhibition test when it was subcutaneously injected, 1 μg kg for 6 d, or added directly to the cotton-pellet. 4. Yunaconitine inhibited the increased vascular permeability caused byacetic acid and histamine, the leucocyte migratory response induced by injection of 1 % carrageenin .1 ml in rat's thoracic cavity.

Escin IIB, a natural saponin compound isolated from the seeds of horse chestnut (Aesculus hippocastanum L.), exhibits biologically positive effects on acute inflammation in animal models. Escin IIB has also demonstrated strong gastroprotective properties by significantly reducing ethanol-induced gastric mucosal lesions, highlighting its potential application in the study of anti-inflammatory mechanisms and gastric mucosal defense pathways in preclinical research.

Lamiide has anti-inflammatory activity in carrageenin-induced paw edema test. It shows lipid peroxidation inhibition on rat-brain phospholipid peroxidation.

3-demethylcolchicine is a natural product isolated from Gloriosa superba.Inhibitory effect on the polymerization of purified bovine brain tubulin.