Home Tools
Log in
Cart

Search Result

Search Results for " cachexia "

16

Compounds

Cat No. Product Name Synonyms Targets
T19470 Nandrolone propionate Others , Androgen Receptor
Nandrolone propionate is an anabolic steroid action primarily consisting of androgenic and nitrogen-retentive properties.
T1284 Megestrol acetate SC10363,BDH1298 Glucocorticoid Receptor , Estrogen/progestogen Receptor , Progesterone Receptor , HIV Protease , Autophagy
Megestrol acetate (BDH1298) is a progestogen with actions and uses similar to those of the progestogens in general. Megestrol acetate also has anti-androgenic properties. It is given by mouth in the palliative treatment ...
T1520 Aliskiren hemifumarate CGP 60536,SPP 100,CGP60536B RAAS , Autophagy
Aliskiren hemifumarate (CGP60536B) is an orally active nonpeptide renin inhibitor with antihypertensive activity.
T69526 PF-07258669 Melanocortin Receptor
PF-07258669 is a selective melanocortin 4 receptor (MC4) antagonist used in the study of cachexia and loss of appetite.
TN5538 6-Methoxykaempferol Others
6-Methoxykaempferol is a flavonoid found in brazilian propolis. 6-Methoxykaempferol has anti-proliferative activity against cancer cells, neuroprotective effects on isolated rat brain synaptosomes and reduces glutathione...
T76774 Ponsegromab PF 06946860 TGF-beta/Smad
Ponsegromab (PF 06946860) is a selective and effective humanized anti-GDF15 antibody inhibitor. Ponsegromab has anti-cachexic activity by binding to GDF15 to prevent its binding to GFRAL, thus disrupting GDF15/GFRAL medi...
T2408 Ostarine MK-2866,GTX-024,Enobosarm Androgen Receptor
Ostarine (MK-2866) is a non-steroidal agent with anabolic activity. Selective androgen receptor modulator (SARM) GTx-024 is designed to work like testosterone, thus promoting and/or maintaining libido, fertility, prostat...
T27986 MCL0129 MCL-0129,MCL 0129
MCL0129, a selective and non-peptidergic melanocortin 4 (MC4) receptor antagonist, is a potential treatment for cachexia.
T80541 TCMCB07 TFA Melanocortin Receptor
TCMCB07 TFA is a cyclic nonapeptide and an orally active, brain-penetrating antagonist of the melanocortin receptor 4 (MC4R), playing a significant role in managing cachexia [1].
T82263 GPR61 Inverse agonist 1
Compound 1, identified as a GPR61 inverse agonist, exhibits an IC50 of 11 nM, rendering it suitable for metabolism and body weight disorder research, including obesity and cachexia [1].
T80540 TCMCB07 Melanocortin Receptor
TCMCB07, a cyclic nonapeptide, serves as an orally active, brain-penetrant antagonist of the melanocortin receptor 4 (MC4R), with significant implications in the management of cachexia [1].
T64163 Aliskiren hydrochloride
Aliskiren (CGP 60536; CGP60536B; SPP 100) hydrochloride is a selective, orally active, renin inhibitor (IC50: 1.5 nM). Cachexia.
T72526 Aliskiren fumarate CGP 60536 fumarate,SPP 100 fumarate,CGP 60536 fumarate ; CGP60536B fumarate ; SPP 100 fumarate,CGP60536B fumarate
Aliskiren fumarate, an orally active, highly potent, and selective renin inhibitor with an IC50 of 1.5 nM, is utilized in the research of hypertension, cardiovascular diseases, and cancer cachexia.
T68276 Macimorelin acetate EP-1572 acetate ; AEZS-130 acetate,AEZS-130 acetate,EP-1572 acetate
Macimorelin Acetate (EP-1572), an orally active growth hormone (GH) secretagogue and a ghrelin receptor (GHSR) agonist, stimulates GH release. It is utilized in research focusing on adult growth hormone deficiency (AGHD)...
T39236 Relamorelin acetate Relamorelin acetate,RM-131 acetate,BIM-28131acetate
Relamorelin (RM-131) acetate is a pentapeptide ghrelin analog that acts as a selective agonist for the ghrelin/growth hormone secretagogue receptor (GHSR). It exhibits a high affinity for the GHS-1a receptor, with a Ki v...
T75262 Relamorelin TFA
Relamorelin (RM-131) TFA, a pentapeptide ghrelin analog, acts as a potent and selective agonist for the ghrelin/growth hormone secretagogue receptor (GHSR), with a K_i of 0.42 nM for the GHS-1a receptor. This compound is...
TargetMol