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(1)
By Target- CDK
- Gamma-secretase(1)
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- Aromatase
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- GPR
- LHRH
- Opioid Receptor
- Oxytocin Receptor
- RAAS
- Reductase
- Thyroid hormone receptor(THR)
- 5-HT Receptor
- Adenosine Receptor
- Adiponectin receptor
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- Apelin receptor
- Arrestin
- Bombesin Receptor
- Bradykinin Receptor
- cAMP
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- CaSR
- CGRP Receptor
- cholecystokinin
- CRFR
- CXCR
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- EBI2/GPR183
- Endothelin Receptor
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- Glucagon Receptor
- GNRH Receptor
- GPCR19
- GPR
- GRK
- GTPase
- Guanylate cyclase
- Hedgehog/Smoothened
- Histamine Receptor
- Kisspeptin
- Leukotriene Receptor
- LPA Receptor
- LPL Receptor
- Melanin-concentrating Hormone Receptor (MCHR)
- Melanocortin Receptor
- Melatonin Receptor
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- Neurokinin receptor
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By Target By ResearchField- Cancer(1)
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Results for "
bt-474/t
" in TargetMol Product Catalog- Inhibitors & Agonists2
- Inhibitory Antibodies1
Dalpiciclib
SHR-6390
T96361637781-04-4
Dalpiciclib (SHR-6390) is a highly selective, orally bioavailable, and comparable potency inhibitor of CDK4 and CKD6 with IC50s of 12.4 nM and 9.9 nM, respectively. Dalpiciclib exerts potent antitumor activity in esophageal squamous cell carcinoma by inhibiting phosphorylated tumor suppressor retinoblastoma protein (Rb) and inducing G1 cell cycle arrest.
- $152
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QTY
MAb604.107
T9901A-1601
MAb604.107 is a human monoclonal antibody targeting NOTCH1. It inhibits the proliferation of primary T-ALL cells and reduces CD34/CD44 expression. MAb604.107 demonstrates antitumor activity in four tumor xenograft mouse models: MDA-MB-231, HCC-1806, BT-474, and HCT-116. It can be utilized in research on T acute lymphoblastic leukemia (T-ALL).
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