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- Inhibitors & Agonists1
- Inhibitory Antibodies1
Briquilimab
JSP-191
T783052574591-89-0
Briquilimab (JSP-191), a non-toxic humanized monoclonal antibody, targets CD117 (c-Kit) to deplete hematopoietic stem cells (HSCs), providing a safe approach for clearing host marrow niche to facilitate adequate donor HSC engraftment and immune reconstitution, primarily in the treatment of severe combined immunodeficiency (SCID) [1].
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