bacillus subtilis

Fraxidin is a class of coumarin. It is isolated from the roots of Jatropha podagrica. It also shows antibacterial activity against Bacillus subtilis with an inhibition zone of 12 mm at a concentration of 20 µg/disk.

1-Decanol inhibits various bacteria and fungi, including Candida albicans, Penicillium, Aspergillus niger, Bacillus subtilis, Propionibacterium, and others.

L-Norvaline is an arginase inhibitor and a non-protein branched-chain amino acid. L-Norvaline has previously been reported as a natural component of the antifungal peptide of Bacillus subtilis. L-Norvaline and other modified branched-chain amino acids have received attention in recent studies because they appear to be incorporated into some recombinant proteins found in E. coli.

Xanthosine is produced by guanine-free mutants of bacteria e.g. Bacillus subtilis, Aerobacter aerogenes. Xanthosine monophosphate is an intermediate in purine metabolism, formed from IMP, and forming GMP.

2-Methylcyclohexa-2,5-diene-1,4-dione exhibits inhibitory activity against cancer cells such as A2780, HT-29, HL-60, and K562 (IC50 = 2.8–12.1 µM) and antibacterial activity against Bacillus subtilis.

Gramicidin (Gramicidine) is an antimicrobial peptide. Gramicidin dimers form ion channel-like pores in the cell membranes and organelles of bacterial and animal cells, allowing inorganic monovalent ions, such as potassium and sodium ions, to pass freely through the pores by diffusion, disrupting the important ionic gradient between membranes and thus killing the cells by various actions. Gramicidin is effective against Gram-positive bacteria such as Bacillus subtilis and Staphylococcus aureus, but is not as effective against Gram-negative bacteria such as Escherichia coli.

Fengycin (fengmycin), a cyclic lipopeptide produced by Bacillus subtilis, is a biosurfactant with antifungal and biodegradable properties.

1-Aminopropan-2-ol is involved in the metabolism of threonine in Bacillus subtilis strains and can be used as a nitrogen source on fungal media.

(2E,4E)-Decadienoic acid, an aliphatic anti-oomycete agent, is present in the coculture of Bacillus subtilis and Trichoderma asperellum [1].

Apigravin, a potent antibacterial compound, demonstrates activity against Bacillus subtilis, exhibiting a minimum inhibitory concentration (MIC) value of 61 μM [1].

Monascorubrin, a compound extracted from the mycelium of Monascus purpureus, exhibits significant antibiotic activity against Bacillus subtilis and Candida pseudotropicalis [1].

Enfumafungin is a triterpenoid glycoside isolated from endophytic fungi, exhibiting antifungal activity against Candida and Aspergillus species by inhibiting (1,3)-β-D-glucan synthesis.

Maximin 15, an antimicrobial peptide originating from toad brain, exhibits activity against Staphylococcus aureus, Escherichia coli, and Bacillus subtilis, with respective minimum inhibitory concentration (MIC) values of 9.4, 18.8, and 75 μg/mL [1].

Maximin 28, an antimicrobial peptide isolated from toad brain tissue, exhibits activity against various bacterial strains, including Staphylococcus aureus, Escherichia coli, and Bacillus subtilis, with respective minimum inhibitory concentrations (MIC) of 4.7, 9.4, and 75 μg/mL [1].

Pycnophorin effectively suppresses Bacillus subtilis and Staphylococcus aureus proliferation, demonstrating identical minimum inhibitory concentration (MIC) values of 25 μM for both bacterial species.

Blepharotriol, a phenolic triterpene isolated from Maytenus blepharodes, exhibits antimicrobial activity, with a minimum inhibitory concentration (MIC) of 8-4 µg/ml against Bacillus subtilis. It also demonstrates cytotoxic activity, with half-maximal inhibitory concentrations (IC50s) of 12.2 µM for HeLa cells, and greater than 20 µM for both Hep-2 and Vero cells [1].

1-Aminopropan-2-ol (Standard) is the standard substance of 1-Aminopropan-2-ol, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. 1-Aminopropan-2-ol is involved in the metabolism of threonine in Bacillus subtilis strains and can be used as a nitrogen source on fungal media.

1-Decanol (Standard) is the standard substance of 1-Decanol, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. 1-Decanol inhibits various bacteria and fungi, including Candida albicans, Penicillium, Aspergillus niger, Bacillus subtilis, Propionibacterium, and others.

Chrysospermin D exhibits antibacterial activity against certain Gram-positive bacteria, including Staphylococcus aureus and Bacillus subtilis, as well as Klebsiella pneumoniae and some yeasts such as Trichophyton ochraceum and Saccharomyces cerevisiae.

Epoxyquinomicin B is an antibiotic isolated from Amycolatopsissp. It exhibits inhibitory activity against Micrococcus luteus, Bacillus subtilis, Pasteurella piscicida, and Staphylococcus aureus, with a minimum inhibitory concentration (MIC) of 6.25-12.5 µg/mL. It also shows cytotoxicity in cancer cells L1210, with an IC50 of 16.3 µg/mL. Additionally, Epoxyquinomicin B demonstrates anti-inflammatory effects on collagen-induced arthritis.

Cyclacidin exhibits activity against Gram-positive bacteria, such as Bacillus subtilis and Gambosia occidentalis, and demonstrates inhibitory effects on Sarcoma 180, among others.

Curromycin B exhibits antibacterial activity against Gram-positive bacteria such as Bacillus subtilis. It also inhibits the replication of human immunodeficiency virus (HIV) and suppresses the proliferation of mouse melanoma B16 and leukemia P388 cells.

γ-Chloronorvaline exhibits antimicrobial activity against Pseudomonas aeruginosa, Serratia, Klebsiella pneumoniae, and Bacillus subtilis in synthetic media, while it shows no effect on Escherichia coli.

Chrysospermin C exhibits antibacterial activity against certain Gram-positive bacteria, including Staphylococcus aureus and Bacillus subtilis, as well as against Klebsiella pneumoniae and some yeasts, such as Pichia ochro-chloron and Saccharomyces cerevisiae.