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By Target- DUB
- Apoptosis(1)
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- Thyroid hormone receptor(THR)
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- Annexin A
- Apelin receptor
- Arrestin
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- Bradykinin Receptor
- cAMP
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- CRFR
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By Target By ResearchField- Cancer(1)
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Results for "
b-ap15
" in TargetMol Product Catalog.- Inhibitors & Agonists2
B-AP15
Cited
NSC 687852
T19321009817-63-3
B-AP15 (NSC-687852)(NSC-687852) is a selective inhibitor of the deubiquitinating enzymes Usp14 and UCHL5 of the 26S proteasome. It blocks the deubiquitinating activity of the 26S proteasome.
- $32
Size
QTY
CitedVLX 1500
(E/Z)-NSC-687852, (E/Z)-b-AP15
T1932L330450-45-8
VLX 1500 is a potent deubiquitinating enzyme (DUBs) inhibitor designed to overcome resistance to traditional proteasome inhibitors. It triggers ER stress-mediated apoptosis by specifically blocking USP14/UCHL5 activity on the 19S regulatory particle, leading to a lethal accumulation of ubiquitinated proteins, widely used in drug target screening for relapsed hematological malignancies.
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