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Results for "

at877

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    4
    TargetMol | Inhibitors_Agonists
Fasudil hydrochloride
HA-1077 hydrochloride, Fasudil HCl, Fasudil (HA-1077) HCl, AT-877 hydrochloride
T3060105628-07-7
Fasudil hydrochloride (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK with Ki of 0.33 μM, 1.0 μM, 9.3 μM and 55 μM, respectively.
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Fasudil
HA-1077, AT877
T1606103745-39-7
Fasudil (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK.
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fasudil dihydrochloride
T61382203911-27-7
Fasudil dihydrochloride, also known as HA-1077 and AT877, is a nonspecific inhibitor of RhoA ROCK. It exhibits inhibitory effects on protein kinases, including ROCK1 with a Ki value of 0.33 μM, as well as ROCK2, PKA, PKC, and PKG with IC 50 values of 0.158 μM, 4.58 μM, 12.30 μM, and 1.650 μM, respectively. Additionally, Fasudil dihydrochloride demonstrates potent Ca 2+ channel blocking activity and acts as a vasodilator [1] [2] [3].
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1-2 weeks
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Fasudil mesylate
T864111001206-62-7
Fasudil mesylate (HA-1077; AT877) is a nonspecific, orally active inhibitor of RhoA ROCK, exhibiting additional inhibitory effects on protein kinases with a K i of 0.33 μM for ROCK1. It shows IC 50 values of 0.158 μM for ROCK2, and 4.58 μM, 12.30 μM, and 1.650 μM for PKA, PKC, and PKG, respectively. Furthermore, Fasudil mesylate acts as a potent Ca 2+ channel antagonist and vasodilator, enhancing its pharmacological profile [1] [2] [3] [4] [5] [6].
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2-4 weeks
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