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as1413

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  • Inhibitors & Agonists
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Amonafide L-malate
T68985618863-54-0
Amonafide L-malate is the malate salt of amonafide, an imide derivative of naphthalic acid, with potential antineoplastic activity. Amonafide intercalates into DNA and inhibits topoisomerase II, resulting in DNA double-strand breaks (DSB) and inhibition of DNA replication and RNA synthesis.
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1-2 weeks
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Amonafide
AS1413, NSC308847, Quinamed, Nafidimide
T633669408-81-7
Amonafide (NSC-308847,AS1413)(AS1413) produces protein-associated DNA-strand breaks through a topoisomerase II-mediated reaction, but does not produce topoisomerase I-mediated DNA cleavage.
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