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Results for "
arq-092
" in TargetMol Product Catalog- Inhibitors & Agonists2
Miransertib
Cited
ARQ-092, AKT inhibitor 2
T34671313881-70-7
Miransertib (ARQ-092) is an orally bioavailable, selective, and potent allosteric Akt inhibitor.
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Citedmiransertib (arq 092) hcl
T222471313883-00-9
Miransertib hydrochloride (ARQ-092 hydrochloride) is a potent, orally bioavailable, selective, and allosteric inhibitor of Akt with an IC50 of 2.7 nM, 14 nM, and 8.1 nM against Akt1, Akt2, and Akt3, respectively. It also shows significant potency against the AKT1-E17K mutant protein and holds promise for research on PI3K AKT-driven tumors and Proteus syndrome. Additionally, Miransertib hydrochloride exhibits efficacy against Leishmania [1, 2].
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