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Results for "
apetx2
" in TargetMol Product Catalog- Inhibitors & Agonists2
- Peptide Products1
APETx2
TP2081713544-47-9
Acid-sensing ion channel 3 (ASIC3) channel blocker (IC50 values are 63 and 175 nM for homomeric rat and human ASIC3 channels). Also inhibits NaV1.8 and NaV1.2 channels (IC50 values are 55 and 114 nM respectively). Demonstrates analgesic properties against
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T75924
APETx2 TFA, a selective and reversible inhibitor of the ASIC3 channel derived from the sea anemone Anthopleura elegantissima, exhibits an IC50 of 63 nM. It operates by directly acting on the external side of the ASIC3 channel. Additionally, APETx2 has been shown to reverse acid-induced and inflammatory pain, as documented in studies [1] [2].
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