amino peg12 boc

Amino-PEG12-Boc, a PEG-based PROTAC linker, is utilized in the synthesis of PROTACs.

Amino-PEG12-CH2-Boc is a PEG-based linker for PROTACs, facilitating the connection of essential ligands necessary for PROTAC formation and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

Boc-NH-PEG12-NHS ester is a PEG derivative composed of an NHS ester, which can react with amino acids or other amine-containing molecules.

t-Boc-N-amido-PEG12-acid is a PEG linker featuring a terminal carboxylic acid and a Boc-protected amino group. The hydrophilic PEG spacer enhances solubility in aqueous media. The terminal carboxylic acid can react with primary amine groups in the presence of activators (such as EDC or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to yield a free amine.