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amg 337

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
AMG-337 monohydrate
T703181643590-78-6
AMG-337 monohydrate is a highly selective small molecule MET inhibitor. Aberrant hepatocyte growth factor (HGF) MET signaling has been implicated in hepatocarcinogenesis, suggesting that MET may serve as an attractive therapeutic target in hepatocellular carcinoma.
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AMG-337
AMG337
T32091173699-31-4
AMG-337 is an effective and highly specific ATP-competitive MET kinase inhibitor. In enzymatic assays, AMG-337(AMG337) inhibits MET kinase activity (IC50: < 5 nM).
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