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  • PARP
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ag-014699

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
Rucaparib
AG-14447, PF-01367338, AG014699
T4463283173-50-2
Rucaparib (PF-01367338) is a PARP protein inhibitor (PARP-1 Ki=1.4 nM) and hexose hexose-6-phosphate dehydrogenase (H6PD) inhibitor with oral activity. Rucaparib exhibits antitumor activity, with activity against desmoplasia-resistant prostate cancer (CRPC).
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Rucaparib Phosphate
AG-014699 phosphate, PF-01367338 phosphate
T6127459868-92-9
Rucaparib Phosphate (PF-01367338 phosphate) is an inhibitor of PARP (Ki: 1.4 nM for PARP1) that is used in clinical therapy to sensitize cancer cells to chemotherapy.
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