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Results for "
afizagabar
" in TargetMol Product Catalog- Inhibitors & Agonists1
Afizagabar
T373881398496-82-6
Afizagabar (S44819) is a first-in-class, competitive, and selective antagonist at the GABA-binding site of the α5-GABAAR, with an IC50 of 585 nM for α5β2γ2 and a Ki of 66 nM for α5β3γ2. It enhances hippocampal synaptic plasticity and exhibits pro-cognitive efficacy [1].
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