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By Target- Potassium Channel
- Drug Metabolite(1)
- NADPH(1)
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Results for "
acetohexamide
" in TargetMol Product Catalog- Inhibitors & Agonists2
Acetohexamide
Gamadiabet, Dymelor, Acetohexamid
T0816968-81-0
Acetohexamide (Acetohexamid) is an intermediate-acting, first-generation sulfonylurea with hypoglycemic activity. It inhibits sulfonylurea receptor 1 (SUR1) linked to the inwardly rectifying potassium channel (KIR6.2) with Ki values of 22.9 and 14.2 μM in HEK293 cells transfected with the human receptor and in rat brain, respectively. Acetohexamide is metabolized in the liver to its active metabolite hydroxyhexamide.
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Hydroxyhexamide
(±)-Hydroxyhexamid
T01503168-01-2
Hydroxyhexamide ((±)-Hydroxyhexamid) is a pharmacologically active metabolite of Acetohexamide, used as a hypoglycemic agent.
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