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UK-5099

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  • Inhibitors & Agonists
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UK-5099
UK 5099, PF-1005023, UK5099
T444156396-35-1
UK-5099 (PF-1005023) is a specific and potent inhibitor of MPC carrier activity, effectively inhibiting pyruvate-dependent oxygen consumption in rat heart mitochondria with an IC50 of 50 nM [1].
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TargetMol | Inhibitor Sale
MPC-IN-1
T89896
MPC-IN-1 (compound 4i), a derivative of UK-5099, is a cyanocinnamate-based inhibitor of the mitochondrial pyruvate transporter (MPC). This compound selectively fosters the development of hair follicle stem cells while not impacting normal cells. It enhances cellular lactate production and has shown significant hair growth promotion in mice, suggesting its potential use in combating hair loss.
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