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Tyrphostin B42

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    1
    TargetMol | Inhibitors_Agonists
AG490
AG 490, Tyrphostin B42, Tyrphostin AG 490, AG-490, Zinc02557947
T2600133550-30-8
AG490 (Tyrphostin B42) is an inhibitor of EGFR (IC50: 0.1 μM). It is 135-fold more selective for EGFR than ErbB2, also inhibits JAK2 with no effect to Lyn, Lck, Syk, Btk, and Src.
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TargetMol | Citations Cited
TargetMol
(E/Z)-AG490
T60624134036-52-5
(E/Z)-AG490 ((E/Z)-Tyrphostin AG490) is a racemic compound comprising the isomers (E)-AG490 and (Z)-AG490. (E)-AG490 functions as a tyrosine kinase inhibitor, targeting EGFR, Stat-3, and JAK2/3.
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6-8 weeks
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