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Search Results for " ta-270 "

1

Compounds

27

Recombinant Proteins

Cat No. Product Name
T28907 TA-270 LS-123351,LS123351
TA-720, a 5-lipoxygenase inhibitor, is used potentially for the treatment of asthma.
Cat No. Product Name Species Source
TMPY-01519 Influenza A H1N1 (A/New Caledonia/20/1999) Hemagglutinin / HA Protein (His) H1N1 HEK293
The influenza viral Hemagglutinin (HA) protein is a homotrimer with a receptor binding pocket on the globular head of each monomer.HA has at least 18 different antigens. These subtypes are named H1 through H18.HA has two functions. Firstly, it allows the recognition of target vertebrate cells, accomplished through the binding to these cells' sialic acid-containing receptors. Secondly, once bound it facilitates the entry of the viral genome into the target cells by causing the fusion of the host ...
TMPY-05918 Influenza A H1N1 (A/Guangdong-Maonan/SWL1536/2019) / (A/Hawaii/70/2019) Hemagglutinin / HA Protein (His) H1N1 HEK293
The influenza viral Hemagglutinin (HA) protein is a homotrimer with a receptor binding pocket on the globular head of each monomer.HA has at least 18 different antigens. These subtypes are named H1 through H18.HA has two functions. Firstly, it allows the recognition of target vertebrate cells, accomplished through the binding to these cells' sialic acid-containing receptors. Secondly, once bound it facilitates the entry of the viral genome into the target cells by causing the fusion of the host ...
TMPJ-00206 TROP-2 Protein, Human, Recombinant (aa 27-274, hFc) Human Human Cells
Tumor associated calcium signal transducer 2 (TACSTD2, TROP-2) is a type I cell surface glycoprotein that is highly expressed on human carcinomas. It was originally identified as an antigen present on human gastrointestinal tumors and is the second of two members of this family. Human and mouse TROP-2 share 87% amino acid (aa) similarity. TROP-2 is capable of transducing an intracellular calcium signal and may play a role in tumor growth. It also has adhesive functions.
TMPY-03903 Neuregulin-1 Protein, Canine, Recombinant (aa 19-240,His) Canine HEK293
Neuregulin 1 or NRG1 is one of four proteins in the neuregulin family that act on the EGFR family of receptors. This growth factor was originally identified as a 44-kD glycoprotein that interacts with the NEU / ERBB2 receptor tyrosine kinase to increase its phosphorylation on tyrosine residues. NRG1 is a trophic factor that has been implicated in neural development, neurotransmission, and synaptic plasticity. NRG1 has multiple isoforms that are generated by the usage of different promoters and a...
TMPY-04485 EphA4 Protein, Human, Recombinant (aa 570-986, His & GST) Human Baculovirus-Insect Cells
EPH receptor A4 (ephrin type-A receptor 4), also known as EphA4, belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family which 16 known receptors (14 found in mammals) are involved: EPHA1, EPHA2, EPHA3, EPHA4, EPHA5, EPHA6, EPHA7, EPHA8, EPHA9, EPHA10, EPHB1, EPHB2, EPHB3, EPHB4, EPHB5, EPHB6. The Eph family of receptor tyrosine kinases (comprising EphA and EphB receptors) has been implicated in synapse formation and the regulation of synaptic function and plasticity6. Eph...
TMPK-00356 IL-27RA/TCCR Protein, Human, Recombinant (His) Human HEK293
IL-27Ra (also known as TCCR and WSX1) as a gene whose expression can induce the transformation of hematopoietic cells. IL-27Ra (IL-27R) is a type I cytokine receptor that functions as the ligand binding component of the receptor for IL-27 and functions with the glycoprotein 130 (gp130) coreceptor to induce signal transduction in response to IL-27.
TMPY-04366 ALK-5 Protein, Human, Recombinant (aa 200-503, His & GST) Human Baculovirus-Insect Cells
Transforming growth factor, beta receptor I, also known as Transforming growth factor-beta receptor type I , Serine / threonine-protein kinase receptor R4, Activin receptor-like kinase 5, SKR4, ALK-5, and TGFBR1, is a single-pass type I membrane protein that belongs to the protein kinase superfamily and TGFB receptor subfamily. TGFBR1 / ALK-5 is found in all tissues examined. It is most abundant in placenta and least abundant in brain and heart. TGF-beta functions as a tumor suppressor by inhibi...
TMPY-04156 Influenza A H3N2 (A/Victoria/210/2009) Hemagglutinin / HA Protein (His) H3N2 Baculovirus-Insect Cells
The influenza viral Hemagglutinin (HA) protein is a homotrimer with a receptor binding pocket on the globular head of each monomer.HA has at least 18 different antigens. These subtypes are named H1 through H18.HA has two functions. Firstly, it allows the recognition of target vertebrate cells, accomplished through the binding to these cells' sialic acid-containing receptors. Secondly, once bound it facilitates the entry of the viral genome into the target cells by causing the fusion of the host ...
TMPY-00298 Influenza A H2N2 (A/Canada/720/2005) Hemagglutinin / HA Protein (His) H2N2 Baculovirus-Insect Cells
The influenza viral Hemagglutinin (HA) protein is a homotrimer with a receptor binding pocket on the globular head of each monomer.HA has at least 18 different antigens. These subtypes are named H1 through H18.HA has two functions. Firstly, it allows the recognition of target vertebrate cells, accomplished through the binding to these cells' sialic acid-containing receptors. Secondly, once bound it facilitates the entry of the viral genome into the target cells by causing the fusion of the host ...
TMPY-03413 PPIL2 Protein, Human, Recombinant (aa 280-457, His) Human E. coli
PPIL2, is an enzyme that belongs to the cyclophilin family. The cyclophilins are peptidylprolyl isomerases and are highly conserved ubiquitous. They play an important role in protein folding, immunosuppression by cyclosporin A, and infection of HIV-1 virions. PPIL2 interacts with the proteinase inhibitor eglin c and is localized in the nucleus. It contains 1 PPIL2 cyclophilin-type domain and 1 U-box domain. PPIL2 accelerate the folding of proteins. It catalyzes the cis-trans isomerization of pro...
TMPY-00251 ICAM5 Protein, Human, Recombinant (aa 1-570,hFc) Human HEK293
TMPY-04237 Neuregulin-1 Protein, Canine, Recombinant (aa 176-240,His) Canine HEK293
Neuregulin 1 or NRG1 is one of four proteins in the neuregulin family that act on the EGFR family of receptors. This growth factor was originally identified as a 44-kD glycoprotein that interacts with the NEU / ERBB2 receptor tyrosine kinase to increase its phosphorylation on tyrosine residues. NRG1 is a trophic factor that has been implicated in neural development, neurotransmission, and synaptic plasticity. NRG1 has multiple isoforms that are generated by the usage of different promoters and a...
TMPY-04386 EphB2 Protein, Human, Recombinant (aa 570-987, His & GST) Human Baculovirus-Insect Cells
Ephrin type-B receptor 2, also known as EphB2, belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family which 16 known receptors (14 found in mammals) are involved: EPHA1, EPHA2, EPHA3, EPHA4, EPHA5, EPHA6, EPHA7, EPHA8, EPHA9, EPHA10, EPHB1, EPHB2, EPHB3, EPHB4, EPHB5, EPHB6. EphB2 receptor tyrosine kinase phosphorylates syndecan-2 and that this phosphorylation event is crucial for syndecan-2 clustering and spine formation. The Eph family of receptor tyrosine kinases (comp...
TMPY-04575 TIE2 Protein, Mouse, Recombinant (aa 770-1122, His & GST) Mouse Baculovirus-Insect Cells
TEK, or TIE-2, is an endothelial cell-specific receptor tyrosine kinase (RTK) that is known as a functioning molecule of vascular endothelial cells. TEK comprises a subfamily of RTK with TIE, and these two receptors play critical roles in vascular maturation, maintenance of integrity and remodeling. Targeted mutagenesis of both Tek and its agonistic ligand, Angiopoietin-1, result in embryonic lethality, demonstrating that the signal transduction pathways mediated by this receptor are crucial for...
TMPY-03296 SHP-1 Protein, Mouse, Recombinant (aa 207-597, His & GST) Mouse Baculovirus-Insect Cells
PTPN6 is an enzyme that belongs to the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. N-terminal part of PTPN6 contains two tandem Src homolog (SH2) domains, which act as protein phospho-tyrosine binding domains, and mediate the interaction of PTPN6 with its substrates. PTPN6 is expressed primarily in hematopoietic cells, and functions as an ...
TMPY-06141 Influenza A H1N1 (A/Wisconsin/588/2019) / (A/Victoria/2570/2019) Hemagglutinin / HA Protein (His) H1N1 HEK293
The influenza viral Hemagglutinin (HA) protein is a homotrimer with a receptor binding pocket on the globular head of each monomer.HA has at least 18 different antigens. These subtypes are named H1 through H18.HA has two functions. Firstly, it allows the recognition of target vertebrate cells, accomplished through the binding to these cells' sialic acid-containing receptors. Secondly, once bound it facilitates the entry of the viral genome into the target cells by causing the fusion of the host ...
TMPY-05874 Influenza A H1N1 (A/Thailand/271/2005) Hemagglutinin / HA Protein (His) H1N1 HEK293
The influenza viral Hemagglutinin (HA) protein is a homotrimer with a receptor binding pocket on the globular head of each monomer.HA has at least 18 different antigens. These subtypes are named H1 through H18.HA has two functions. Firstly, it allows the recognition of target vertebrate cells, accomplished through the binding to these cells' sialic acid-containing receptors. Secondly, once bound it facilitates the entry of the viral genome into the target cells by causing the fusion of the host ...
TMPK-00543 DLL3 Protein, Cynomolgus, Recombinant (aa 27-477, His) Cynomolgus HEK293
Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands. DLL3 inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm (By similarity).
TMPY-06525 FAP Protein, Human, Recombinant (aa 27-760,His) Human Baculovirus-Insect Cells
Seprase, also known as 17 kDa melanoma membrane-bound gelatinase , Fibroblast activation protein alpha, Integral membrane serine protease and FAP, is a single-pass type II membrane protein which belongs to thepeptidase S9B family. Seprase / FAP is found in cell surface lamellipodia, invadopodia and on shed vesicles. Seprase / FAP appears to act as a proteolytically active 17-kDa dimer, consisting of two 97-kDa subunits. It is a member of the group type II integral serine proteases, which include...
TMPK-00542 DLL3 Protein, Cynomolgus, Recombinant (aa 27-488, His) Cynomolgus HEK293
Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands. DLL3 inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm (By similarity).

Recombinant Proteins

Influenza A H1N1 (A/New Caledonia/20/1999) Hemagglutinin / HA Protein (His)
TMPY-01519
Species: H1N1
Source: HEK293
Influenza A H1N1 (A/Guangdong-Maonan/SWL1536/2019) / (A/Hawaii/70/2019) Hemagglutinin / HA Protein (His)
TMPY-05918
Species: H1N1
Source: HEK293
TROP-2 Protein, Human, Recombinant (aa 27-274, hFc)
TMPJ-00206
Species: Human
Source: Human Cells
Neuregulin-1 Protein, Canine, Recombinant (aa 19-240,His)
TMPY-03903
Species: Canine
Source: HEK293
EphA4 Protein, Human, Recombinant (aa 570-986, His & GST)
TMPY-04485
Species: Human
Source: Baculovirus-Insect Cells
IL-27RA/TCCR Protein, Human, Recombinant (His)
TMPK-00356
Species: Human
Source: HEK293
ALK-5 Protein, Human, Recombinant (aa 200-503, His & GST)
TMPY-04366
Species: Human
Source: Baculovirus-Insect Cells
Influenza A H3N2 (A/Victoria/210/2009) Hemagglutinin / HA Protein (His)
TMPY-04156
Species: H3N2
Source: Baculovirus-Insect Cells
Influenza A H2N2 (A/Canada/720/2005) Hemagglutinin / HA Protein (His)
TMPY-00298
Species: H2N2
Source: Baculovirus-Insect Cells
PPIL2 Protein, Human, Recombinant (aa 280-457, His)
TMPY-03413
Species: Human
Source: E. coli
ICAM5 Protein, Human, Recombinant (aa 1-570,hFc)
TMPY-00251
Species: Human
Source: HEK293
Neuregulin-1 Protein, Canine, Recombinant (aa 176-240,His)
TMPY-04237
Species: Canine
Source: HEK293
EphB2 Protein, Human, Recombinant (aa 570-987, His & GST)
TMPY-04386
Species: Human
Source: Baculovirus-Insect Cells
TIE2 Protein, Mouse, Recombinant (aa 770-1122, His & GST)
TMPY-04575
Species: Mouse
Source: Baculovirus-Insect Cells
SHP-1 Protein, Mouse, Recombinant (aa 207-597, His & GST)
TMPY-03296
Species: Mouse
Source: Baculovirus-Insect Cells
Influenza A H1N1 (A/Wisconsin/588/2019) / (A/Victoria/2570/2019) Hemagglutinin / HA Protein (His)
TMPY-06141
Species: H1N1
Source: HEK293
Influenza A H1N1 (A/Thailand/271/2005) Hemagglutinin / HA Protein (His)
TMPY-05874
Species: H1N1
Source: HEK293
DLL3 Protein, Cynomolgus, Recombinant (aa 27-477, His)
TMPK-00543
Species: Cynomolgus
Source: HEK293
FAP Protein, Human, Recombinant (aa 27-760,His)
TMPY-06525
Species: Human
Source: Baculovirus-Insect Cells
DLL3 Protein, Cynomolgus, Recombinant (aa 27-488, His)
TMPK-00542
Species: Cynomolgus
Source: HEK293
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