T7545

6-Aminonicotinamide (6-AN) is a well-established inhibitor of the NADP+-dependent enzyme.

P-orlandin, a fungal metabolite, effectively impedes Plasmodium falciparum infection in mosquitoes by preventing FREP1 from binding to gametocytes or ookinetes [1].

Cytoglobosin C, a derivative of cytochalasan, demonstrates significant cytotoxic effects on SGC-7901 and A549 cell lines, with an inhibitory concentration (IC50) of less than 10 μM [1].

11-epi-Chaetomugilin I, a metabolite identified in Chaetomium globosum, demonstrates notable cytotoxic activity against several cell lines, including the murine P388 and L1210 leukemia cell lines, the human HL-60 leukemia cell line, and the human KB epidermoid carcinoma cell line [1].

Penicitide A, a marine secondary metabolite, demonstrates moderate cytotoxic effects against the pathogen A. brassicae and the human hepatocellular liver carcinoma (HepG2) cell line [1].

Dendryphiellin D, a compound extracted from the plant pathogenic fungus Septoria rudbeckiae found on the halophyte Karelinia caspia, significantly reduces nitric oxide (NO) [1] production.

Septeremophilane E, a compound extracted from Septoria rudbeckiae—a plant pathogenic fungus found on the halophyte Karelinia caspia—significantly reduces nitric oxide (NO) production [1].

(-)-10,11-Dihydroxyfarnesol, isolated from the endolichenic fungus Cryptomarasmius aucubae, significantly inhibits nitric oxide (NO) production [1].

Canadensolide, an antifungal metabolite of *Penicillium canadense*.