T7470

6-Chloropurine (6-Chloro-9H-purine) is a building block in chemical synthesis,with Antitumor activities.

Mal-VC-PAB-(N-Me-amide-C3)-ADU-S100 triethylamine is a linker–payload small molecule of an immune-stimulating antibody conjugate (ISAC), consisting of the STING agonist (ADU-S100) and a cleavable linker. Mal-VC-PAB-(N-Me-amide-C3)-ADU-S100 triethylamine can be used in cancer research.

A18-Iso5-2DC18 (compound A18), a lipidoid, enhances mRNA protein expression and induces a robust immune response [1].

5'-ODMT cEt N-Bz A Phosphoramidite Amidite, a locked nucleic acid (LNA) analogue, exhibits hybridization and mismatch discrimination capabilities similar to LNA, and shows resistance to exonuclease digestion [1].

5'-ODMT cEt G Phosphoramidite Amidite is a potent nucleic acid analog with exceptional safety and significant antisense activity, as demonstrated in studies [1] [2].

5'-ODMT cEt N-Bzm5 C Phosphoramidite Amidite is a potent nucleic acid analog and a modified antisense oligonucleotide [1].

5'-ODMT cEt m5U Phosphoramidite Amidite, a locked nucleic acid (LNA) analog, demonstrates exceptional safety and antisense activity [1] [2].

PROTAC FLT3/CDK9 degrader-1, a potent dual degrader of FLT3 and CDK9, effectively induces apoptosis and targets protein degradation of FLT3 and CDK9. This compound holds research potential for FLT3-ITD mutated AML [1].

β2AR/M-receptor agonist-1 (example 131), a muscarinic antagonist and β2 adrenoceptor agonist (MABA), exhibits dual potency towards β2 adrenoceptor and muscarinic receptor, with an EC50 value of 9.2 nM for β2 adrenoceptor and a Ki value of 30.2 nM for the muscarinic receptor, and an EC50 value of 4.0 nM highlighting its MABA activity [1].