T7395

Lys-CoA TFA, a selective p300 histone acetyltransferase (HAT) inhibitor (IC 50 =50-500 nM), exhibits a specificity that exceeds 100-fold over PCAF (IC 50 =200 μM). This compound effectively suppresses transcriptional activation dependent on p300 HAT activity [1] [2].

Neomycin C, an isomeric component of the Neomycin complex, is a 2-DOS-containing aminoglycoside that comprises neomycin A, B, and C. It is notably less potent, exhibiting approximately half the activity of neomycin B [1] [2].

Leucinostatin, a mixture of components A and B, constitutes the primary elements of a unique nonapeptide complex synthesized by Paecilomyces lilacinus, functioning as antibiotics [1].

Potassium Clavulanate Mixture with Silicon Dioxide (1:1) is a compound consisting of an equal parts ratio, specifically one part Potassium Clavulanate to one part Silicon Dioxide, presented in a powdered form [1].

Amoxicillin (trihydrate) mixed with potassium clavulanate (4:1) is a broad-spectrum antibiotic that exhibits strong oral absorption. It functions by inhibiting the biosynthesis of polypeptides in bacterial cell walls, which effectively halts cell growth, demonstrating its antimicrobial activity [1] [2] [3].

PROTAC Bcl-xL degrader-1 is a potent PROTAC composed of a Bcl-xL (Bcl-2 family member) ligand-binding group, a linker, and an IAP E3 ligases binding group, demonstrating effectiveness as a Bcl-xL degrader. It exhibits toxicity towards human platelets and MyLa 1929 cells, with IC50 values of 62 nM and 8.5 μM, respectively [1].