T7061

Duloxetine is an inhibitor of serotonin-norepinephrine reuptake(Ki of 4.6 nM),with treatment of major depressive disorder and generalized anxiety disorder.

Iso-SLR 080811 is an isomer of SLR 080811, suitable for relevant research in the life sciences. SLR080811 is a selective SphK2 inhibitor (Ki=1.3 μM) that elevates blood S1P levels in wild-type mice, reduces S1P levels in sphk1 knockout mice, and leaves S1P levels unchanged in SphK2 knockout mice.

E 3040 is a dual inhibitor of 5-lipoxygenase and thromboxane synthase with oral activity. E 3040 exhibits anti-inflammatory activity .

ATSP-7041 is a novel potent and selective dual inhibitor of mdm2 (ki = 0.9 nm) and mdmx (ki = 7 nm)

TAS-303 is a selective norepinephrine reuptake inhibitor which displays significant norepinephrine transporter (NET) inhibitory activity toward serotonin or dopamine transporters. Radioligand-binding studies showed that TAS-303 selectively and potently inhibited [3H]norepinephrine binding to the human NET.

ACT-672125 is a Potent CXCR3 Antagonist with Therapeutic Potential in Autoimmune Diseases. ACT-672125 showed good physicochemical properties and safety profile. In a proof-of-mechanism model of lung inflammation, ACT-672125 inhibited the recruitment of CXCR3 expressing T cells into the inflamed lung in a dose-dependent manner.

GP-1-515 is an adenosine kinase inhibitor with anti-inflammatory effects.

Duloxetine-D7 is a deuterated compound of Duloxetine. Duloxetine (T7061) has a CAS number of 116539-59-4. Duloxetine (T7061) is an inhibitor of serotonin-norepinephrine reuptake (Ki of 4.6 nM),with treatment of major depressive disorder and generalized anxiety disorder.