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(1)
By Target- Apoptosis
- MEK(1)
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- Oxytocin Receptor
- RAAS
- Reductase
- Thyroid hormone receptor(THR)
- 5-HT Receptor
- Adenosine Receptor
- Adiponectin receptor
- Adrenergic Receptor
- Amylin Receptor
- Annexin A
- Apelin receptor
- Arrestin
- Bombesin Receptor
- Bradykinin Receptor
- cAMP
- Cannabinoid Receptor
- CaSR
- CGRP Receptor
- cholecystokinin
- CRFR
- CXCR
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- EBI2/GPR183
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- Glucagon Receptor
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- GPCR19
- GPR
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- GTPase
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- Sigma receptor
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- AhR
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- Antiviral
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- Cytokine release
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- gp120/CD4
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- Immunology/Inflammation related
- Interleukin
- IRAK
- LTR
- MALT
- MRP
- MyD88
- NADPH-oxidase
- NO Synthase
- NOD
- NOD-like Receptor (NLR)
- NOS
- Nrf2
- PD-1/PD-L1
- PGE Synthase
- Prostaglandin Receptor
- Pyroptosis
- Reactive Oxygen Species
- ROS
- STING
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- EGFR
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Results for "
T5857
" in TargetMol Product Catalog- Inhibitors & Agonists1
Trametinib (DMSO solvate)
Cited
Trametinib DMSO solvate, Trametinib dimethyl sulfoxide, JTP-74057 (DMSO solvate), GSK-1120212 (DMSO solvate)
T58571187431-43-1
Trametinib (DMSO solvate) (GSK-1120212 (DMSO solvate)) is a highly potent and selective MEK inhibitor that specifically inhibits MEK1/2 (IC50: 2 nM).
- $41
Size
QTY
Cited
TMID-0691
Trametinib-13C6 is a 13C labeled version of Trametinib. Trametinib (GSK1120212; JTP-74057) is an orally active MEK inhibitor with IC50 values of 2 nM for MEK1 and MEK2. It has the capability to activate autophagy and induce apoptosis.
- Inquiry Price
Size
QTY
JTP-74057, GSK1120212
T2125871700-17-3
Trametinib (GSK1120212) is a MEK inhibitor that inhibits MEK1 and MEK2 (IC50=0.7/0.9 nM) with ATP non-competitive and oral activity. Trametinib activates autophagy and induces apoptosis.
- $31
Size
QTY
CitedTMID-0655
Trametinib-d4 is the deuterated form of Trametinib. Trametinib (GSK1120212; JTP-74057) is an orally bioavailable MEK inhibitor, effectively inhibiting MEK1 and MEK2 with an IC50 of 2 nM. Additionally, Trametinib can activate autophagy and induce apoptosis.
- Inquiry Price
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QTY
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