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T3S0209

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  • Inhibitors & Agonists
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    TargetMol | All_Pathways
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    TargetMol | Natural_Products
Vincristine
T3S020957-22-7
Vincristine binds to tubulin and inhibits the formation of microtubules, thereby inhibiting mitosis of the cancer cell. Vincristine can be used as a microtubule-destabilizing agent for research on the treatment of hematologic cancers, such as leukemia and
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Vincristine sulfate
Leurocristine sulfate, Leurocristine, 22-Oxovincaleukoblastine sulfate
T12702068-78-2
Vincristine sulfate is an alkaloidal natural product that binds to microtubule proteins and inhibits the formation of microtubules, thereby inhibiting mitosis in tumor cells. Vincristine sulfate is used as a microtubule destabilizing agent in research studies for the treatment of hematologic neoplasms such as leukemias and lymphomas, as well as in studies related to sarcomas in children.
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TargetMol | Citations Cited
Vincristine-d3 sulfate
TMID-12371246817-10-6
Vincristine-d3 (sulfate) is the deuterated form of Vincristine sulfate. Vincristine sulfate is an antitumor vinca alkaloid that inhibits the formation of microtubules in the mitotic spindle, resulting in the arrest of dividing cells at metaphase. It binds to microtubules with a Ki of 85 nM.
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