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(1)
By Target- DNA/RNA Synthesis
- HCV Protease(1)
- Nucleoside Antimetabolite/Analog(1)
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Results for "
T38237
" in TargetMol Product Catalog- Inhibitors & Agonists1
2′-O-Methylcytidine
T382372140-72-9
2'-O-Methylcytidine is a nucleoside derivative and an inhibitor of hepatitis C virus (HCV) non-structural protein 5B (NS5B; IC50= 3.8 μM).1It inhibits HCV replication in a replicon assay (IC50= 21.2 μM).
1.Migliaccio, G., Tomassini, J.E., Carroll, S.S., et al.Characterization of resistance to non-obligate chain-terminating ribonucleoside analogs that inhibit hepatitis C virus replication in vitroJ. Bio. Chem.278(49)49164-49170(2003)
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