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(2)
By Target- Melatonin Receptor
- MT Receptor(1)
- Potassium Channel(1)
- Others(1)
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Results for "
T3495
" in TargetMol Product Catalog- Inhibitors & Agonists3
- Isotope Products1
Tasimelteon
Cited
VEC-162, BMS-214778
T3495609799-22-6
Tasimelteon (BMS-214778) is a melatonin receptor agonist that is used for the treatment of non-24 hour sleep-wake disorder in blind individuals.
- $38
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QTY
CitedTasimelteon-D5
T700351962124-51-1
Tasimelteon-D5 is intended for use as an internal standard for the quantification of tasimelteon by GC- or LC-MS. Tasimelteon (T3495) is a melatonin (MT) receptor agonist. It selectively binds MT1 and MT2 receptors over a panel of 160 additional receptors and enzymes at 10 µM. Tasimelteon (T3495) inhibits forskolin-induced cAMP accumulation with EC50 values of 0.79 and 1 nM in NIH3T3 cells expressing the MT1 or MT2 receptor, respectively. Formulations containing tasimelteon have been used in the treatment of non-24-hour sleep-wake disorder.
- $878
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