T21703

4-Chlorophenylguanidine hydrochloride is a potent and selective inhibitor of urokinase.

PROTACD16-M1P2 is an orally active PKMYT1 PROTAC degrader with a DC50 of 0.7 nM. It also exhibits inhibitory activity against PKMYT1 with an IC50 of 7.6 nM and inhibits pCDK1 with an IC50 of 9 nM. PROTACD16-M1P2 demonstrates significant antitumor activity in mouse models and is applicable for breast cancer research.

(6R,8S,10R,11S,13S,14R)-17-(2-Acetoxyacetyl)-11-hydroxy-6,10,13-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl propionate' is a PROTAC linker utilized in the synthesis of PROTAC molecules.

CRBN ligand-318 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), used to recruit the cereblon protein. It can be attached to a target protein ligand via a linker to form a PROTAC.

tert-Butyl 4-(3-hydroxypropyl)tetrahydropyridine-1(2H)-carboxylate is a PROTAC linker used in the synthesis of PROTAC molecules.

Desamino lenalidomide-piperidine-C-piperazine hydrochloride is an E3 ligase ligand-linker conjugate that includes a CRBN-based ligand and a linker, useful for synthesizing PROTAC.

3-(Piperidin-4-yl)propan-1-amine is a PROTAC linker used in the synthesis of PROTAC molecules.

CRBN ligand-473 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), utilized for recruiting the cereblon protein. Through a linker, CRBN ligand-473 can attach to a target protein ligand to form a PROTAC.

CRBN ligand-210 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit cereblon proteins. It can be connected to a target protein ligand via a linker to form PROTAC.

2-(2,6-Dimethylpiperazin-1-yl)ethan-1-amine is a PROTAC linker used in the synthesis of PROTAC molecules.

CRBN ligand-655 is a ligand of the E3 ubiquitin ligase cereblon (CRBN), designed to recruit cereblon proteins. It can be linked through a linker to a target protein ligand to form a PROTAC.