T20866

Tribromsalan (3,5,4'-Tribromosalicylanilide) is an inhibitor of Mycobacterium tuberculosis and abscess bacillus, inhibiting IkappaBalpha phosphorylation to suppress NF-kappaB signaling.

CG428-NEG is a negative control for TRK degraders. CG428 inhibits cell growth and reduces levels of TPM3-TRKA.

uPSEM792 hydrochloride is an agonist of PSAM4-GlyR.

(S,R,S)-AHPC-C5-NH2 (VH032-C5-NH2) dihydrochloride is a synthetic E3 ligase ligand-linker conjugate, incorporating a VH032-based VHL ligand and a linker. This compound is utilized in the synthesis of PROTAC degraders targeting ERRα.

(S,R,S)-AHPC-C7-aminedihydrochloride is the dihydrochloride salt form of (S,R,S)-AHPC-C7-amine. The compound (S,R,S)-AHPC-C7-amine is a synthetic E3 ligase ligand-linker (E3ligaseligand-linker conjugate) that includes a VHL ligand based on VH032 and one linker. It is utilized for synthesizing PROTAC degraders targeting ERRα.

Lenalidomide 4'-PEG1-amine dihydrochloride is a Lenalidomide-based Cereblon ligand designed for the recruitment of CRBN protein. It can be linked to a protein ligand via a linker to form a PROTAC.

Lenalidomide 4'-PEG2-amine dihydrochloride is a Cereblon ligand derived from Lenalidomide, designed to recruit CRBN proteins. This compound can be conjugated with a protein ligand through a linker to create a PROTAC.